Page 5 - IPA_11_2021
P. 5

DUPHASTON WITH ANTI-ANDROGENIC ACTIVITY                                                                  1
                                   ®



                   DUPHASTON has less pronounced anti-androgenic
                                           ®

                             pre-receptor effects than progesterone                        1





                     PROGESTERONE                            DYDROGESTERONE

                                  CH 3                                         CH 3

                              CH  3  C   O                                 CH  3  C   O

                    CH                                            CH
                        3                                            3

                         H                                             H             C
            O                  A     B     C     D       O                                 D
                                                                           A   B



                                                      Dydrogesterone is a retroprogesterone, a stereoisomer
                                                         of progesterone, with an additional double-bond
                                                                    between carbon 6 and 7  1














                                                                                                       - (MAT 03 2020) IQVIA data


       References: 1. Schindler AE, Campagnoli C, Druckmann R, et al. Classification and Pharmacology of progestins. Maturitas 2008;61(1-2):171-180.
                 ®
        S4  Duphaston  10 mg tablets. Each tablet contains 10 mg dydrogesterone. Registration number: South Africa: S/21.8.2/165.
       For full prescribing information refer to the approved professional information by the Medicines Regulatory Authority.
       Date of Publication of this promotional material: June 2021. Promotional Review Number: SAF2192526.
       Abbott Laboratories S.A. (Pty) Ltd. Co. Reg. No. 1940/014043/07. Abbott Place, 219 Golf Club Terrace, Constantia Kloof, 1709. Tel: +27 11 858 2000.
   1   2   3   4   5   6   7   8   9   10